About Alpha 2 Macroglobulin Therapy

Alpha 2 Macroglobulin (A2M) is a protease inhibitor that occurs naturally in the blood and inhibits the actions of proteins that damage joints and cartilage. Concentrated A2M injections help manage osteoarthritis and other degenerative conditions.

The A2M used in our therapy contains a significant, industry-leading 7 to 10-fold increase in platelet concentration compared to whole blood.

For over a decade, high-level athletes have used A2M therapy to avoid surgery and benefit from shortened recovery periods.  

How it Works



After identifying the tailored A2M solution needed to treat your pain, a blood sample is drawn and run through a centrifuge which separates the blood into its components.


Plasma Concentation

Plasma, which contains the beneficial platelets, is collected and further refined using a centrifuge for a double spin and then a special filter to concentrate vital platelets and healing molecules.



A2M treats degeneration and inflammation directly at the source by attaching to damaging proteins and inactivating them. The neutralized proteins reduce cartilage deterioration and treat degeneration and inflammation directly at the source.



Some patients begin experiencing pain relief shortly after their first A2M injection. Significant pain relief is normally felt after two weeks, and the healing process continues with full benefits usually felt after six to eight weeks.

A2M Can Treat:

  • Osteoarthritis
  • Bursitis
  • Ligament sprains and tears
  • Tendonitis and tendinosis
  • Plantar fasciitis
  • Tennis or Golfer’s Elbow
  • Degenerative disc or joint disease